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Innovators

of the Artificial Womb-

C.H.O.P

  An Artificial Womb Lamb was created by Researchers at the Children's Hospital of Philadelphia around May of 2017. It was created so that fetuses could grow outside the mother's uterus to prevent birth complications or for further growth of premature babies to mimic a womb. 

Research at CHOP:


   

At the Children's Hospital of Philadelphia Dr. Flakes a surgeon there. He has been testing this artificial womb on 8 lambs. It replicates the womb and the conditions that occur inside of it. He hopes that with the success of the 8 lambs being in the womb that it will eventually be able to be used on babies within 3- 5 years. While in the womb they are kept in a dark room with noises replicated by the mother. A normal pregnancy lasts about 40 weeks. This womb is to be designed for those born 23 or 24 weeks into pregnancy so that there is a chance for survival when they are born.

Hong- Ching Liu

    Hong- Ching Liu, the director of the Reproductive Endocrine Laboratory at Cornell University was the first to experiment with the artificial womb. In 2001, Liu’s lab started growing human tissue  made of cells from the lining of the uterus. Dr. Hung- Ching Liu and her team removed several cells from a woman’s uterus and by using hormones and growth factors. They have successfully have been able to grow the cells.In 2003, a mouse embryo grew almost to full term by adding engineered endometrium (inner lining of  uterus) tissue to a bio-engineered, extra-uterine “scaffold”. Up to now, Dr. Hung-Ching Liu has recently incubated a human embryo, for ten days in an artificial womb, because her work is limited by legislation that imposes a 14-day limit on research project of this kind of experiment. Her goal now is to be able to create a a functioning external womb with her team.

   Yoshinori Kuwabara

   Over in Juntendo University Japan, a Japanese professor Dr. Yoshinori Kuwabara has gestated several goat embryos in a machine that contains amniotic fluid inside the tanks. Dr. Yoshinori Kuwabara has conducted multiple experiments using goat fetuses. The goat fetuses were transferred to the machine after three weeks of gestation. This was equivalent to transplanting a human fetus at the end of the first trimester. This technique, called extra-uterine fetal incubation, this involves placing the goat fetus in a plastic container of warmed amniotic-like fluid. After that it is supplied with nutrients through a tube inserted its umbilical cord.

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